Dörrler J, Wahba A
Abteilung für Gefässchirurgie, Technischen Universität München.
Herz. 1991 Dec;16(6):425-33.
In surgical practice, about 15% of all emboli are visceral emboli. Diagnosis is frequently delayed or established at autopsy.
The most common cause are atrial arrhythmias with intraatrial thrombus formation, less frequently, ventricular thrombus after myocardial infarction or in an aneurysm, emboli from vegetations due to infective endocarditis, from atrial myxomas and, occasionally, from arteriosclerotic plaques, aortic tumors or mural aortic thrombi. Cholesterol embolism: Cholesterol embolism or the multiple cholesterol emboli syndrome (MCES) is of particular importance. There are three large groups of symptoms: a peripheral manifestation with livedo reticularis, renal manifestation with progressive renal failure and visceral manifestation with intestinal bleeding and segmental infarction. The only possibility for treatment is surgical removal of the source of embolization through infrarenal aortic replacement or suprarenal aortic arteriectomy. Renal embolism: Acute traumatic interruption of the renal perfusion in otherwise healthy subjects usually leads to loss of the organ due to the limited ischemia tolerance. On the other hand, the results of renal artery embolectomy can be favorable even after 24 hours of ischemia since, as a rule, embolism does not completely occlude the vascular lumen and, in patients with arteriosclerosis, collateral vessels are usually present. The clinical presentation usually encompasses acute onset of flank or back pain, tenderness to percussion of the kidneys, nausea, vomiting and hematuria. In 25% of the cases, the course of renal embolism is bland. The low specificity of the complaints requires delineation of high-risk patients. At the first level of diagnostics, other causes of the complaints should be ruled out with catheterization of the bladder, ultrasound, intravenous pyelography and computer tomography with intravenous contrast medium.(ABSTRACT TRUNCATED AT 250 WORDS)
在外科手术中,所有栓子中约15%为内脏栓子。诊断常常延迟,或在尸检时才得以确立。
最常见的病因是伴有心房内血栓形成的房性心律失常,较少见的是心肌梗死后或动脉瘤内的心室血栓、感染性心内膜炎所致赘生物的栓子、心房黏液瘤的栓子,偶尔还有动脉粥样硬化斑块、主动脉瘤或主动脉壁血栓的栓子。胆固醇栓塞:胆固醇栓塞或多发性胆固醇栓子综合征(MCES)尤为重要。有三大组症状:外周表现为网状青斑,肾脏表现为进行性肾衰竭,内脏表现为肠道出血和节段性梗死。唯一的治疗方法是通过肾下主动脉置换或肾上主动脉切除术手术切除栓塞源。肾栓塞:在原本健康的受试者中,急性创伤性肾灌注中断通常会因缺血耐受性有限而导致肾脏丧失。另一方面,即使在缺血24小时后,肾动脉取栓术的结果也可能良好,因为通常栓塞不会完全阻塞血管腔,而且在患有动脉硬化的患者中通常存在侧支血管。临床表现通常包括突发的胁腹或背部疼痛、肾脏叩击痛、恶心、呕吐和血尿。在25%的病例中,肾栓塞的病程较为隐匿。这些症状的低特异性需要明确高危患者。在诊断的第一阶段,应通过膀胱插管、超声、静脉肾盂造影和静脉注射造影剂的计算机断层扫描排除其他病因。(摘要截取自250字)