Murta Eddie F C, Perfeito Paula B, Oliveira Tânia M, Michelin Márcia A, Maluf Paulo J
Research Institute of Oncology/Discipline of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Avenida Getúlio Guaritá s/n, Uberaba, Minas Gerais, Brazil.
Arch Gynecol Obstet. 2008 Jan;277(1):43-6. doi: 10.1007/s00404-007-0420-7. Epub 2007 Jul 25.
This study aimed to investigate the influence of endocervical pH on vaginal pH, and also the changes in these pH values following hysterectomy and cold-knife conization. Vaginal pH is important for maintaining the equilibrium of the vaginal microflora.
Two groups of women were studied: the first (n = 20, median age 45, range 33-50 years-old), before and after hysterectomy (without ovariectomy) for myomatosis; the second group (n = 18, median age 38.5, range 37-65 years-old), before and after cold-knife conization for cervical intraepithelial neoplasia (CIN) grade II or III. Four samples (before and 90 days after surgery) were collected from the women by means of swabs: (1) anterior vaginal fornix, (2) posterior vaginal fornix, (3) posterior wall of lower vagina, and (4) endocervix (except in cases after hysterectomy). The pH was measured using a digital pHmeter (Sentron).
We observed that endocervical pH was less acidic than were all the vaginal locations measured, before both surgeries. After both surgeries, all vaginal pH measurements were higher, but without reaching statistical significance. Endocervical pH correlated with vaginal pH.
We concluded that recent hysterectomy does not alter vaginal pH and that vaginal and endocervical pH values are related.
本研究旨在调查宫颈管pH值对阴道pH值的影响，以及子宫切除术后和冷刀锥切术后这些pH值的变化。阴道pH值对于维持阴道微生物群的平衡很重要。
研究了两组女性：第一组（n = 20，中位年龄45岁，范围33 - 50岁），因子宫肌瘤行子宫切除术（未切除卵巢）前后；第二组（n = 18，中位年龄38.5岁，范围37 - 65岁），因宫颈上皮内瘤变（CIN）II级或III级行冷刀锥切术前后。通过棉签从这些女性身上采集四个样本（手术前和手术后90天）：（1）阴道前穹窿，（2）阴道后穹窿，（3）阴道下后壁，以及（4）宫颈管（子宫切除术后的病例除外）。使用数字pH计（Sentron）测量pH值。
我们观察到，在两种手术前，宫颈管的pH值比所测量的所有阴道部位的pH值酸性都弱。两种手术后，所有阴道pH值测量结果均升高，但未达到统计学显著性。宫颈管pH值与阴道pH值相关。
我们得出结论，近期子宫切除术不会改变阴道pH值，且阴道和宫颈管pH值相关。
