Iwai F, Sostman H D, Evans A J, Nadel S N, Hedlund L W, Beam C A, Charles H C, Spritzer C E
Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
Invest Radiol. 1991 Dec;26(12):1071-8. doi: 10.1097/00004424-199112000-00007.
Using a 1.5 T magnetic resonance imaging (MRI) system, cine phase-contrast and magnitude images were obtained in three phantoms that simulated different anatomic configurations of aortic dissection. The dissection phantoms were made of compliant materials, and pulsatile flow was used in all experiments. Phantoms differed only in the location of the fenestration between the true and false lumens (I: an upstream "entry" only, II: both upstream "entry" and downstream "re-entry," and III: a downstream "entry" only). Flow jets, flap motion, and wave propagation were clearly visualized in cine MR images of each phantom, and quantitatively analyzed with reference to the stimulated cardiac cycle of the pump. Flow in the false lumen was always bidirectional. Upstream and downstream flow waves collided and dispersed within the false lumen. Flow through the false lumen was the same in phantoms I and II, and least in phantom III. The average area of the true lumen was largest in phantom III and smallest in I. Phantom I had the highest overall flow rate in the false lumen and greatest change in false lumen size during the cardiac cycle, while the downstream "entry" phantom had the lowest of both parameters. Flow phenomena in aortic dissections can be studied by cine phase-contrast MRI.
使用1.5T磁共振成像（MRI）系统，在模拟主动脉夹层不同解剖结构的三个模型中获取电影相位对比图像和幅度图像。夹层模型由顺应性材料制成，所有实验均采用脉动流。模型仅在真腔和假腔之间开窗的位置有所不同（I：仅上游“入口”，II：既有上游“入口”又有下游“再入口”，III：仅下游“入口”）。在每个模型的电影磁共振图像中均可清晰观察到血流喷射、瓣叶运动和波传播，并参照泵的模拟心动周期进行定量分析。假腔内的血流始终是双向的。上游和下游的血流波在假腔内碰撞并分散。模型I和II中通过假腔的血流量相同，模型III中最少。真腔的平均面积在模型III中最大，在I中最小。模型I在假腔内的总血流量最高，心动周期内假腔大小变化最大，而下游“入口”模型的这两个参数均最低。通过电影相位对比MRI可以研究主动脉夹层中的血流现象。
