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[局部加热过程中人体皮肤血流调节系统变化的评估]

[Assessment of the changes in regulatory systems of human's skin blood flow during local heating].

作者信息

Krasnikov G V, Tankanag A V, Koniaeva T N, Piskunova T N, Chemeris N K

出版信息

Ross Fiziol Zh Im I M Sechenova. 2007 Apr;93(4):394-401.

PMID:17654864
Abstract

The mechanisms of thermal regulation of skin blood flow during local heating to 35, 40 and 45 'C have been studied by the method of laser Doppler flowmetry in healthy volunteers. To estimate the state of microvascular bed the continuous wavelet-transform spectral analysis has been used. The amplitudes of fluxmotions in the range of blood flow active modulation significantly increase during local heating to 35 degrees C. The amplitudes of blood flow oscillations in the ranges of cardiorhythm and respiratory rhythm increase during local heating to 40 degrees C. The high amplitude oscillations in the range of myogenic activity are maintained. The amplitude of oscillations in the range of endothelial activity distinctly decreases and the oscillations in the range of neurogenic activity are inhibited. Local heating to 45 degrees C results in a significant decreasing of the oscillation amplitudes in the range of myogenic activity, and the amplitudes of cardio- and respiratory spectral components amount to their peak values among the temperatures of local heating under study.

摘要

通过激光多普勒血流仪法,在健康志愿者中研究了局部加热至35、40和45摄氏度时皮肤血流的热调节机制。为评估微血管床状态,采用了连续小波变换频谱分析。局部加热至35摄氏度时,血流主动调节范围内的通量运动幅度显著增加。局部加热至40摄氏度时,心搏节律和呼吸节律范围内的血流振荡幅度增加。肌源性活动范围内的高振幅振荡得以维持。内皮活动范围内的振荡幅度明显降低,神经源性活动范围内的振荡受到抑制。局部加热至45摄氏度导致肌源性活动范围内的振荡幅度显著降低,在研究的局部加热温度中,心脏和呼吸频谱成分的幅度达到峰值。

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