Zugor Vahudin, Schott Günter E, Labanaris Apostolos P
Department of Urology, University of Erlangen Medical Center, Erlangen, Germany.
Urology. 2007 Jul;70(1):157-60. doi: 10.1016/j.urology.2007.02.068.
To report our experience with 10 cases of pediatric xanthogranulomatous pyelonephritis and review the literature regarding this relatively uncommon disease.
The records of 10 patients presenting to our institution with xanthogranulomatous pyelonephritis between 1996 and 2006 were examined. The mode of presentation, clinical and radiologic findings, blood count, blood chemistry, urine culture results, operative findings, and histologic findings of the affected kidney were recorded.
Staging was performed according to the classification of Malek and Elder. Through radiologic and operative investigations our patients were classified as Stage 1 (n = 1), Stage 2 (n = 6), and Stage 3 (n = 3). Simple nephrectomy was performed in all 10 patients.
Previously the diagnosis of xanthogranulomatous pyelonephritis was normally based on pathologic assessment, most commonly after nephrectomy. During the last decade, however, increasingly sensitive radiologic investigations (sonography, four-phase computed tomography, and magnetic resonance imaging) in combination with clinical suspicion have made its preoperative diagnosis possible. Surgical intervention still remains the cornerstone of treatment for this relatively uncommon disease.
报告我们对10例儿童黄色肉芽肿性肾盂肾炎的诊治经验，并复习有关这种相对罕见疾病的文献。
查阅1996年至2006年间在我院就诊的10例黄色肉芽肿性肾盂肾炎患者的病历。记录其临床表现方式、临床及影像学检查结果、血常规、血液生化、尿培养结果、手术所见以及患肾的组织学检查结果。
根据Malek和Elder的分类法进行分期。通过影像学和手术检查，我们的患者被分为1期（n = 1）、2期（n = 6）和3期（n = 3）。10例患者均接受了单纯肾切除术。
以往黄色肉芽肿性肾盂肾炎的诊断通常基于病理评估，最常见于肾切除术后。然而，在过去十年中，越来越敏感的影像学检查（超声、四期计算机断层扫描和磁共振成像）与临床怀疑相结合，使其术前诊断成为可能。手术干预仍然是这种相对罕见疾病治疗的基石。
