焦虑和抑郁情绪与身体症状负担有关吗?一项针对住院晚期癌症患者的研究。

Are anxiety and depressed mood related to physical symptom burden? A study in hospitalized advanced cancer patients.

作者信息

Teunissen S C C M, de Graeff A, Voest E E, de Haes J C J M

机构信息

Department of Medical Oncology, University Medical Center, Utrecht, The Netherlands.

出版信息

Palliat Med. 2007 Jun;21(4):341-6. doi: 10.1177/0269216307079067.

Abstract

BACKGROUND

Anxiety and depressed mood are common symptoms in hospitalized advanced cancer patients. It is often presumed that anxiety and depression affect the occurrence and experience of physical symptoms.

PURPOSE

To analyse the relation between anxiety, depressed mood and the presence and intensity of physical symptoms.

PATIENTS AND METHODS

Anxiety and depressed mood were assessed in a hospitalized advanced cancer population (n = 79) primarily by the Hospital Anxiety and Depression Scale (HADS), and also by a single-item question ;Are you anxious and/or depressed?' and by the Edmonton Symptom Assessment System (ESAS). Physical symptoms were assessed by a semi-structured interview and by the ESAS.

RESULTS

Thirty-four percent of the patients reported anxiety, 56% depressed mood and 29% both, as assessed by the HADS. The correlations between HADS, the single-item question and the ESAS were low. No association was found between anxiety or depressed mood and the presence of physical symptoms. Patients who were anxious or depressed had higher ESAS scores for insomnia and drowsiness; scores for pain, anorexia, asthenia, nausea and dyspnea were independent of anxiety and/or depressed mood.

CONCLUSION

The relationship between anxiety, depressed mood and the presence and intensity of physical symptoms in hospitalized advanced cancer patients is very limited.

摘要

背景

焦虑和抑郁情绪是晚期癌症住院患者的常见症状。人们通常认为焦虑和抑郁会影响身体症状的发生和体验。

目的

分析焦虑、抑郁情绪与身体症状的存在及强度之间的关系。

患者与方法

对一组晚期癌症住院患者(n = 79)进行焦虑和抑郁情绪评估,主要采用医院焦虑抑郁量表(HADS),同时采用单项问题“你是否焦虑和/或抑郁?”以及埃德蒙顿症状评估系统(ESAS)。通过半结构化访谈和ESAS对身体症状进行评估。

结果

根据HADS评估,34%的患者报告有焦虑,56%有抑郁情绪,29%两者皆有。HADS、单项问题与ESAS之间的相关性较低。未发现焦虑或抑郁情绪与身体症状的存在之间存在关联。焦虑或抑郁的患者在失眠和嗜睡方面的ESAS评分较高;疼痛、厌食、乏力、恶心和呼吸困难的评分与焦虑和/或抑郁情绪无关。

结论

晚期癌症住院患者的焦虑、抑郁情绪与身体症状的存在及强度之间的关系非常有限。

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