Coulter I, Frewin S, Krassas G E, Perros P
Endocrine Unit, Level 6, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK.
Eur J Endocrinol. 2007 Aug;157(2):127-31. doi: 10.1530/EJE-07-0205.
Patients with thyroid eye disease, Graves' orbitopathy (GO), often appear distressed and it is likely that features of the condition such as disturbances in visual function, orbital discomfort and alterations in facial appearance can impart significant psychological morbidity upon the patient, which in turn can be detrimental to their quality of life. When considering the psychological impact of GO, two elements of the disease are important. The disfiguring changes to the eyes and face can have a direct effect upon psychological health, while physical aspects of the disease such as altered visual acuity, diplopia, orbital pain and lacrimation may influence psychological function as a secondary phenomenon, due to interference with daily living. Evidence appears to confirm the anecdotal impression of many clinicians dealing with GO patients that the prevalence of psychological morbidity in this patient group is high. A 'biopsychosocial' approach to care that addresses biological and psychosocial functioning as major determinants of health is an appropriate strategy when treating patients with GO.
患有甲状腺眼病（Graves眶病，GO）的患者常常显得痛苦不堪，而该病症的一些特征，如视觉功能障碍、眼眶不适以及面部外观改变，很可能会给患者带来严重的心理问题，进而损害他们的生活质量。在考虑GO的心理影响时，该疾病的两个因素很重要。眼睛和面部的毁容性变化会直接影响心理健康，而疾病的身体方面，如视力改变、复视、眼眶疼痛和流泪，可能由于干扰日常生活而作为继发现象影响心理功能。有证据似乎证实了许多治疗GO患者的临床医生的轶事印象，即该患者群体中心理问题的患病率很高。当治疗GO患者时，采用一种“生物心理社会”的护理方法，将生物和心理社会功能作为健康的主要决定因素来处理，是一种合适的策略。
