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心脏病重症监护病房患者需氧革兰氏阴性菌分离株对15种不同抗生素的耐药率较高。

High resistance rate against 15 different antibiotics in aerobic gram-negative bacteria isolates of cardiology intensive care unit patients.

作者信息

Küçükates E, Kocazeybek B

机构信息

University of Istanbul, Institute of Cardiology, Istanbul, Turkey.

出版信息

Indian J Med Microbiol. 2002 Oct-Dec;20(4):208-10.

PMID:17657072
Abstract

Aerobic gram negative bacteria were isolated and examined microbiologically from various clinical samples of 602 patients hospitalized between January 1997 and December 2000 in surgical and coronary intensive care units (ICUs). A total of 827 isolates were obtained from 602 patients. The majority of microorganisms were isolated from the respiratory tract (50.3%) and blood (39.9%). Pseudomonas spp. were the most frequently isolated gram negative species (32.7%), followed by Acinetobacter spp. (24.0%) and Klebsiella pneumoniae (19.4%). High resistance rates to all antibiotics studied were observed. Imipenem and meropenem were the most effective antibiotics against gram negatives.

摘要

1997年1月至2000年12月期间,在外科和冠心病重症监护病房(ICU)住院的602例患者的各种临床样本中分离出需氧革兰氏阴性菌,并进行了微生物学检查。共从602例患者中获得827株分离菌。大多数微生物分离自呼吸道(50.3%)和血液(39.9%)。假单胞菌属是最常分离出的革兰氏阴性菌(32.7%),其次是不动杆菌属(24.0%)和肺炎克雷伯菌(19.4%)。观察到对所有研究抗生素的高耐药率。亚胺培南和美罗培南是对抗革兰氏阴性菌最有效的抗生素。

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