2006年印度医学研究理事会生物医学科学奖：生物固态核磁共振，方法与应用
ICMRBS founder's medal 2006: biological solid-state NMR, methods and applications.
作者信息
Baldus Marc
机构信息
Research Group Solid-state NMR, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Gottingen, Germany.
出版信息
J Biomol NMR. 2007 Sep;39(1):73-86. doi: 10.1007/s10858-007-9177-3. Epub 2007 Jul 27.
Solid-state NMR (ssNMR) provides increasing possibilities to study structure and dynamics of biomolecular systems. Our group has been interested in developing ssNMR-based approaches that are applicable to biomolecules of increasing molecular size and complexity without the need of specific isotope-labelling. Methodological aspects ranging from spectral assignments to the indirect detection of proton-proton contacts in multi-dimensional ssNMR are discussed and applied to (membrane) protein complexes.
固态核磁共振（ssNMR）为研究生物分子系统的结构和动力学提供了越来越多的可能性。我们团队一直致力于开发基于ssNMR的方法，这些方法适用于分子尺寸和复杂性不断增加的生物分子，而无需进行特定的同位素标记。本文讨论了从光谱归属到多维ssNMR中质子-质子接触的间接检测等方法学方面，并将其应用于（膜）蛋白复合物。
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