Klin Monbl Augenheilkd. 2007 Jul;224(7):559-66. doi: 10.1055/s-2007-963356.
The basic conditions in the management of exudative age-related macular degeneration have changed considerably since the last statement of the German professional associations in 2006. While Pegaptanib was approved in Germany already in 2006 Ranibizumab was approved for the treatment of exudative macular degeneration in Germany in February 2007. More over the quality assurance regulations for the photodynamic treatment of choroidal neovascularizations with Verteporfin were modified including the treatment of occult lesions and implementing a simplified classification of extra- and subfoveal lesions. Consequently modification of the recommendations for the non-surgical treatment of exudative age-related macular degeneration appeared inevitable.
自德国专业协会于2006年发布上一份声明以来,渗出性年龄相关性黄斑变性的管理基本情况已发生了相当大的变化。虽然培加他尼已于2006年在德国获批,但兰尼单抗于2007年2月在德国获批用于治疗渗出性黄斑变性。此外,用维替泊芬进行脉络膜新生血管光动力治疗的质量保证规定也进行了修改,包括隐匿性病变的治疗以及对黄斑中心凹外和黄斑中心凹下病变实施简化分类。因此,修改渗出性年龄相关性黄斑变性非手术治疗的建议似乎是不可避免的。