Mir Olivier, Albiges Laurence, Arkwright Sylviane, Duboc Denis, Massault Pierre-Philippe, Tenenbaum Florence, Touzé Emmanuel, Menasché Philippe, Vacher-Lavenu Marie-Cécile, Goldwasser François, Alexandre Jérôme
Department of Oncology, Assistance Publique - Hôpitaux de Paris, Hôpital Cochin, University Paris 5, Faculty of Medicine, Paris, France.
Gynecol Oncol. 2007 Sep;106(3):622-5. doi: 10.1016/j.ygyno.2007.04.024. Epub 2007 Jul 23.
Non-bacterial thrombotic endocarditis is a severe complication of cancer, rarely reported in gynecologic tumors. However, it can be inaugural and lead to complex diagnostic pathways.
A 40-year-old woman presented with a stroke, related to an endocarditis. The valvular vegetation was surgically removed, and a malignant node was resected. A PET-scan led to the diagnosis of a myometrial tumor, which was found to be a primitive neuroectodermal tumor (PNET). The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, and systemic chemotherapy which allowed a complete remission of tumoral and cardio-vascular symptoms.
To our knowledge, this is the first case report of a PNET of the myometrium revealed by cardio-vascular symptoms.
非细菌性血栓性心内膜炎是癌症的一种严重并发症，在妇科肿瘤中很少见。然而，它可能是首发症状并导致复杂的诊断路径。
一名40岁女性因心内膜炎引发中风。通过手术切除了瓣膜赘生物，并切除了一个恶性结节。正电子发射断层扫描（PET）检查诊断为子宫肌层肿瘤，结果发现是原始神经外胚层肿瘤（PNET）。患者接受了全腹子宫切除术及双侧输卵管卵巢切除术，并进行了全身化疗，使肿瘤和心血管症状完全缓解。
据我们所知，这是首例因心血管症状而发现的子宫肌层PNET病例报告。
