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抑郁症患者的睡眠障碍与自杀观念

Sleep disorders and suicidal ideation in patients with depressive disorder.

作者信息

Chellappa Sarah Laxhmi, Araújo John Fontenele

机构信息

Post-Graduate Program in Health Sciences, Center of Health Sciences, Federal University of Rio Grande Do Norte, Av. Gal Gustavo Cordeiro de Farias, s/n, CEP 59010-180, Natal, RN, Brazil.

出版信息

Psychiatry Res. 2007 Oct 31;153(2):131-6. doi: 10.1016/j.psychres.2006.05.007. Epub 2007 Jul 20.

Abstract

An intrinsic association between suicidal ideation and sleep disorders in patients with depressive disorder has been observed in recent studies. This study was conducted in order to examine the relationship between suicidal ideation and sleep disorders, such as insomnia and excessive sleepiness, in outpatients with major depressive disorder. Seventy patients with diagnoses of major depressive disorder were interviewed and assessed with the Sleep Habits Questionnaire and the Beck Scale for Suicidal Ideation (SSI). Data analyses were performed through descriptive analysis, Students t-test, Chi-square test and logistic regression model, with a statistical significance of 5%. In this study, depressed patients had high SSI scores (6.12+/-2.67), particularly for active suicidal ideation (1.61+/-0.39) and specific plans for suicide components (1.51+/-0.40). Depressed patients with insomnia had significantly higher SSI scores (7.39+/-2.84), in relation to patients with excessive sleepiness (3.68+/-1.73). Furthermore it was observed that insomniac patients had significantly higher scores on the following components: active suicide ideation, specific plans for suicide and previous suicide attempts. The results of multivariate analysis showed that only insomnia had a significant association with suicidal ideation. Thus, sleep disturbances, particularly insomnia, should be considered in the assessment of suicidal risk in outpatients with depressive disorder.

摘要

近期研究观察到,抑郁症患者的自杀意念与睡眠障碍之间存在内在关联。本研究旨在探讨重度抑郁症门诊患者的自杀意念与失眠、过度嗜睡等睡眠障碍之间的关系。对70例诊断为重度抑郁症的患者进行访谈,并使用睡眠习惯问卷和贝克自杀意念量表(SSI)进行评估。数据分析通过描述性分析、学生t检验、卡方检验和逻辑回归模型进行,统计学显著性水平为5%。在本研究中,抑郁症患者的SSI得分较高(6.12±2.67),尤其是主动自杀意念(1.61±0.39)和自杀具体计划部分(1.51±0.40)。与过度嗜睡的患者(3.68±1.73)相比,患有失眠的抑郁症患者的SSI得分显著更高(7.39±2.84)。此外,观察到失眠患者在以下方面得分显著更高:主动自杀意念、自杀具体计划和既往自杀未遂。多因素分析结果显示,只有失眠与自杀意念存在显著关联。因此,在评估抑郁症门诊患者的自杀风险时,应考虑睡眠障碍,尤其是失眠。

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