Perbet S, Trouiller P, Paugam-Burtz C, Denninger M-H, Mantz J
Service d'anesthésie-réanimation-urgences-Smur, hôpital Beaujon, Assistance publique-Hôpitaux de Paris, Clichy, France.
Ann Fr Anesth Reanim. 2007 Sep;26(9):791-4. doi: 10.1016/j.annfar.2007.05.002. Epub 2007 Jul 20.
Skin necrosis is a rare complication in intensive care unit. A case-report of nadroparine-induced skin necrosis and thrombocytosis in a patient with traumatic paraplegia is reported. This case emphasised the difficulty in diagnosis despite absence of thrombopenia. A skin necrosis could suggest the diagnosis and a substitutive therapy must be administrated after heparin therapy withdrawal. A thrombocytosis is a little reported complication of low-molecular-weight heparins without complication.