Ben-Chetrit E, Putterman C, Naparstek Y
Department of Internal Medicine A, Hadassah University Hospital, Ein-Kerem, Jerusalem, Israel.
J Rheumatol. 1991 Oct;18(10):1635-7.
A patient with systemic lupus erythematosus complicated by refractory bilateral pleural effusions is described. High dose corticosteroids with azathioprine, as well as intrapleural instillation of corticosteroids, proved ineffective in management. As our patient remained severely symptomatic and required repeated thoracocentesis, a therapeutic trial of intravenous immunoglobulins (IVIG) was attempted. IVIG had a beneficial effect, although of a transient and partial nature. Despite the results achieved, it seems that IVIG has limited value in treating lupus pleural effusion.
本文描述了一名患有系统性红斑狼疮并伴有难治性双侧胸腔积液的患者。高剂量皮质类固醇联合硫唑嘌呤，以及胸腔内注射皮质类固醇，在治疗中均被证明无效。由于我们的患者症状严重且需要反复胸腔穿刺，因此尝试进行静脉注射免疫球蛋白（IVIG）的治疗试验。IVIG产生了有益效果，尽管是短暂和部分性的。尽管取得了这些结果，但IVIG在治疗狼疮性胸腔积液方面的价值似乎有限。
