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鞍区及鞍上区肿瘤病例的内分泌学评估(第二篇报告);——关于术后垂体功能(作者译)

[Endocrinological evaluation of sellar and suprasellar tumor cases (the 2nd report);--on postoperative pituitary function (author's transl)].

作者信息

Uozumi T, Mori S, Watanabe M, Takimoto N, Mogami H

出版信息

No Shinkei Geka. 1976 Jan;4(1):73-8.

PMID:176607
Abstract

Fifty-six cases of sellar and suprasellar tumors were examined endocrinologically before and 3 weeks after surgery. 1) Hyporeactive cases of GH & ACTH were more frequently found in pituitary adenoma (100% and 23% respectively than in craniopharyngioma (86% and 14% respectively) before surgery. 2) GH secretion was impaired 3 weeks after surgery in all the cases. 3) ACTH secretion impaired preoperatively in 5 cases of pituitary adenoma improved in 3 cases 3 weeks after surgery. 4) Hyporeactivity of LH, FSH and TSH was found more frequently after surgery than before. 5) Almost all the cases of tuberculum sellae meningioma were endocrinologically normal before surgery. 6) ACTH, LH, FSH and prolactin secretion in cases of tuberculum sellae meningioma was not impaired after surgery, but TSH secretion in these cases became hyporeative in 4 of 5 cases after surgery.

摘要

对56例鞍区和鞍上肿瘤患者在手术前及术后3周进行了内分泌学检查。1)术前,垂体腺瘤中生长激素(GH)和促肾上腺皮质激素(ACTH)反应低下的病例比颅咽管瘤更常见(分别为100%和23%,而颅咽管瘤分别为86%和14%)。2)术后3周所有病例的GH分泌均受损。3)术前5例垂体腺瘤中ACTH分泌受损,术后3周有3例有所改善。4)术后促黄体生成素(LH)、促卵泡生成素(FSH)和促甲状腺激素(TSH)反应低下比术前更常见。5)几乎所有鞍结节脑膜瘤病例术前内分泌功能正常。6)鞍结节脑膜瘤病例术后ACTH、LH、FSH和催乳素分泌未受损,但这些病例中5例有4例术后TSH分泌变得反应低下。

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