Komatsu H, Horiguchi T, Enzan K, Satoh W, Shouji K, Suzuki M
Department of Anesthesiology, Akita University School of Medicine.
Masui. 1991 Nov;40(11):1736-8.
We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy. In three patients without neuromuscular disorders, T1 was 85% of control and fade was not observed, while in this case T1 was 40% of the control and TOFR was decreased to 50%. We conclude that isoflurane has a good muscle relaxation effect in this disease and, we could manage without administering any muscle relaxants.
我们在肌强直性营养不良患者的神经肌肉传递监测下，采用异氟烷进行全甲状腺切除术的麻醉管理。在3例无神经肌肉疾病的患者中，T1为对照值的85%，未观察到衰减，而在该病例中，T1为对照值的40%，强直后计数比值（TOFR）降至50%。我们得出结论，异氟烷在这种疾病中具有良好的肌肉松弛作用，并且我们可以在不使用任何肌肉松弛剂的情况下进行管理。
