Rojas J I, Zurrú M C, Romano M, Patrucco L, Cristiano E
Neurology Department, Italian Hospital of Buenos Aires, Buenos Aires, Argentina.
Eur J Neurol. 2007 Aug;14(8):895-9. doi: 10.1111/j.1468-1331.2007.01841.x.
Old age groups have different risk profile and stroke features compared to younger groups. Our aim was to examine the risk factor profile and stroke subtype in patients older than 80 years with ischemic stroke. Data of 535 patients with ischemic stroke or transient ischemic attack (TIA) were prospectively recorded. Cardiovascular risk factors and stroke subtype in individuals aged 80 years or older were compared with patients under 80. Of 535 patients a total of 179 were over 80 years (33.5%). The mean age was 84.4 +/- 4.4 years (61.8%; 111 women). The most common risk factors included hypertension (82.7%) and hyperlipidemia (40.2%). Lacunar stroke was the most frequent subtype of stroke (41.7%). When the groups were compared, we observed the following risk factors more frequently in the group older than 80: female patients (P = <0.001), hypertension (OR = 1.62), atrial fibrillation (OR = 2.64); whereas diabetes (OR = 0.54), hyperlipidemia (OR = 0.57), smoking (OR = 0.17) and obesity (OR = 0.58) were more frequent in the group younger than 80. In the old group we found a high incidence of ischemic stroke in women. We also found a higher frequency of hypertension and atrial fibrillation. The available and future epidemiological data will provide a better knowledge about the effect of typical risk factors in old people.
与年轻群体相比，老年群体具有不同的风险特征和中风特点。我们的目的是研究80岁以上缺血性中风患者的风险因素概况和中风亚型。前瞻性记录了535例缺血性中风或短暂性脑缺血发作（TIA）患者的数据。将80岁及以上个体的心血管风险因素和中风亚型与80岁以下患者进行比较。在535例患者中，共有179例年龄超过80岁（33.5%）。平均年龄为84.4±4.4岁（61.8%；111名女性）。最常见的风险因素包括高血压（82.7%）和高脂血症（40.2%）。腔隙性中风是最常见的中风亚型（41.7%）。比较两组时，我们发现80岁以上组中以下风险因素更为常见：女性患者（P =<0.001）、高血压（OR = 1.62）、心房颤动（OR = 2.64）；而糖尿病（OR = 0.54）、高脂血症（OR = 0.57）、吸烟（OR = 0.17）和肥胖（OR = 0.58）在80岁以下组中更为常见。在老年组中，我们发现女性缺血性中风的发病率较高。我们还发现高血压和心房颤动的发生率较高。现有的和未来的流行病学数据将使我们更好地了解典型风险因素对老年人的影响。
