Improving the finite element forward model of the human head by warping using elastic deformation.

As the use of realistic geometry in the forward model of electrical impedance tomography (EIT) of brain function appears to improve image reconstruction, the generation of patient-specific finite element meshes has been the subject of much recent work. This paper presents a more rapid method of generating more geometrically accurate finite element meshes of the human head by warping existing meshes such that the surface boundary beneath the electrodes closely matches that of the subject with minimal degradation to the quality of the mesh. Pre-existing meshes of spheres and adult head models incorporating key internal anatomical features are warped, using elastic deformation, to match a phantom latex tank incorporating a real skull. The algorithm is described and tests are carried out to optimize the key parameters to ensure minimal degradation of mesh quality and distortion of internal features. Results show that the algorithm operating with the optimum parameters produces meshes of sound quality and could represent an important step in the timely and productive creation of forward models in clinical applications.