Silva Márcia Thereza, Piedade Roberto, Ribeiro Pedro, Fonseca Léa Mirian B da, Pellini Marcos Pinto, Cagy Maurício
Laboratório de Mapeamento Cerebral e Integração Sensório-Motora, Instituto de Psiquiatria do Rio de Janeiro, Universidade Federal do Rio de Janeiro, Brasil.
Arq Neuropsiquiatr. 2007 Jun;65(2B):476-81. doi: 10.1590/s0004-282x2007000300022.
The objective of the present study was to evaluate the cerebral blood flow in the cerebellar (4 sub-regions) and pre-frontal cortex, when subjects were in rest and during a motor task performance. The sample consisted of 8 healthy subjects, male or female, between 23 and 36 of age. The visuo-motor task - implicit memory - requires the subjects to navigate and swerve a graphic submarine from missiles that run on the screen. Semi-quantitative analysis with brain SPECT (99mTc-ECD) was used to evaluate regional perfusion. The results revealed an increased activity in all areas of interest during motor task. In conclusion, four sub-regions of cerebellar cortex and both pre-frontal hemispheres showed a simultaneous activation during task. Moreover, our findings suggest as seen in previous experiments that the central nervous system operates in a parallel fashion, in order to integrate sensory and motor information.
本研究的目的是评估受试者在休息和执行运动任务时小脑（4个亚区域）和前额叶皮质的脑血流量。样本包括8名年龄在23至36岁之间的健康受试者，男女不限。视觉运动任务——内隐记忆——要求受试者操纵一艘图形潜艇避开在屏幕上运行的导弹。使用脑单光子发射计算机断层扫描（99mTc-ECD）进行半定量分析，以评估局部灌注。结果显示，在运动任务期间，所有感兴趣区域的活动均增加。总之，小脑皮质的四个亚区域和两个前额叶半球在任务期间同时激活。此外，我们的研究结果表明，正如之前的实验所示，中枢神经系统以并行方式运作，以便整合感觉和运动信息。
