抽动障碍与注意力缺陷多动障碍共病儿童的快速眼动睡眠改变：多动症状的影响
REM-sleep alterations in children with co-existence of tic disorders and attention-deficit/hyperactivity disorder: impact of hypermotor symptoms.
作者信息
Kirov Roumen, Banaschewski Tobias, Uebel Henrik, Kinkelbur Jörg, Rothenberger Aribert
机构信息
Institute of Physiology, Bulgarian Academy of Sciences, Acad. G. Bonchev Str. 23, 1113, Sofia, Bulgaria.
出版信息
Eur Child Adolesc Psychiatry. 2007 Jun;16 Suppl 1:45-50. doi: 10.1007/s00787-007-1006-4.
PURPOSE
To characterize precisely the sleep pattern in children with co-existence of TD + ADHD.
METHODS
By means of polysomnography, sleep pattern was investigated in 19 children with TD + ADHD unmedicated before and during study and 19 healthy controls, matched for age, gender, and intelligence.
RESULTS
Compared with healthy controls, children with TD + ADHD displayed shorter REM sleep latency and increased REM sleep duration. There was a negative correlational relationship between these REM-sleep alterations and they were determined by hyperactivity symptoms.
CONCLUSIONS
Sleep in children with coexistence of TD + ADHD may be characterized by an elevated REM sleep drive. Common mechanisms are suggested to underpin hypermotor symptoms and REM sleep regulation.
目的
精确描述抽动秽语综合征（TD）合并注意力缺陷多动障碍（ADHD）儿童的睡眠模式。
方法
通过多导睡眠图，对19名未用药的TD合并ADHD儿童在研究前和研究期间的睡眠模式进行了调查，并与19名年龄、性别和智力相匹配的健康对照者进行了比较。
结果
与健康对照者相比，TD合并ADHD儿童的快速眼动（REM）睡眠潜伏期较短，REM睡眠时间增加。这些REM睡眠改变之间存在负相关关系，且由多动症状决定。
结论
TD合并ADHD儿童的睡眠可能以REM睡眠驱动力升高为特征。提示存在共同机制支撑多动症状和REM睡眠调节。
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