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[重症烧伤监护病房住院烧伤患者中分离出的铜绿假单胞菌的流行病学特征及抗生素敏感性]

[Epidemiological profile and antibiotic susceptibility of Pseudomonas aeruginosa isolates within the burned patient hospitalized in the intensive care burn unit].

作者信息

Lamia Thabet, Bousselmi K, Saida Ben Redjeb, Allah Messadi Amen

机构信息

Service de réanimation des brûlés, Hôpital Aziza Othmana, Tunis de Tunis.

出版信息

Tunis Med. 2007 Feb;85(2):124-7.

Abstract

BACKGROUND

Pseudomonas aeruginosa plays a predominant role as an etiological agent involved in serious infections in burned patients. Treatment of these infections is frequently complicated by antibiotic resistance, a problem that is is increasing in recent years.

AIM

The objective of this study is to analyze epidemiological profile and antibiotic susceptibility of P. aeruginosa isolates within the burned patients admitted in our intensive care department.

METHODS

During a period of 4 years (2000/2003), 828 burn patients were admitted.

RESULTS

The survey of antibiotic susceptibility of P. aeruginosa showed high percentages of resistance to the different antibiotics. 60.9% of strains were resistant to piperacillin, 53.4% to ceftazidime, 37.6% to imipenem, 70.6% to cefsulodine, 59.3% to tobramycin, 80% to gentamicin, 62.4% to amikacin and 53.4% to ciprofloxacin.

CONCLUSION

It is necessary to implement urgent measures to prevent the spreading of this multiresistant strain. These measures include: sensible limitation of the use of antimicrobial agent, strict disinfection and hygienic procedures.

摘要

背景

铜绿假单胞菌是烧伤患者严重感染的主要病原体。这些感染的治疗常常因抗生素耐药性而变得复杂,近年来这一问题日益严重。

目的

本研究的目的是分析我院重症监护病房收治的烧伤患者中铜绿假单胞菌分离株的流行病学特征及抗生素敏感性。

方法

在4年期间(2000/2003年),共收治828例烧伤患者。

结果

铜绿假单胞菌抗生素敏感性调查显示,对不同抗生素的耐药率很高。60.9%的菌株对哌拉西林耐药,53.4%对头孢他啶耐药,37.6%对亚胺培南耐药,70.6%对磺苄西林耐药,59.3%对妥布霉素耐药,80%对庆大霉素耐药,62.4%对阿米卡星耐药,53.4%对环丙沙星耐药。

结论

有必要采取紧急措施防止这种多重耐药菌株的传播。这些措施包括:合理限制抗菌药物的使用、严格的消毒和卫生程序。

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