Grupenmacher F, Silva F M, Abib F C, Grupenmacher L, Silva A C, de Almeida P T
Department of Ophthalmology, Federal University of Paraná, Brazil.
Ophthalmologica. 1991;203(1):12-6. doi: 10.1159/000310219.
The authors suggest the determination of antibody against HIV in vitreous humor as a screening technique for AIDS carriers, specially in cases of corneal transplantation when the eye bank could make the examinations required and in cases when drawing blood after death becomes difficult. Ten eyes of patients having died of AIDS-related causes were studied and 100% of the samples tested were found to be positive. False-positive results were eliminated by the study of a group of 90 eyes of patients dead from nonrelated causes; the results were all negative. Therefore, no discrepancy was noticed between the examination of the blood and the vitreous humor. A description is made of a technique which uses a special trocar that enables the examination to be made without contamination with blood. The authors conclude that the determination of antibodies in vitreous humor is a choice to be considered as a postmortem examination because it can be easily obtained and its results are reliable.
作者建议将玻璃体液中抗HIV抗体的检测作为艾滋病携带者的一种筛查技术，特别是在眼库能够进行所需检测的角膜移植病例中，以及在死后采血困难的情况下。对10例死于艾滋病相关原因患者的眼睛进行了研究，发现100%的检测样本呈阳性。通过对90例死于非相关原因患者的眼睛进行研究，排除了假阳性结果；结果均为阴性。因此，血液检测和玻璃体液检测之间未发现差异。文中描述了一种使用特殊套管针的技术，该技术能够在不被血液污染的情况下进行检测。作者得出结论，玻璃体液中抗体的检测是一种可考虑作为尸检的选择，因为它易于获取且结果可靠。
