von Falck Christian, Rosenthal Herbert, Gratz Klaus F, Galanski Michael
Department of Diagnostic Radiology, Hannover Medical School, Hannover, Germany.
Clin Nucl Med. 2007 Aug;32(8):640-2. doi: 10.1097/RLU.0b013e3180a1ad09.
A 12-year-old girl was diagnosed with Hodgkin's lymphoma and underwent conventional cross-sectional imaging for initial staging. Chemotherapy was given according to standard pediatric protocols. At the end of therapy, an F-18 FDG PET/CT examination was performed to evaluate the therapeutic response. The scan demonstrated focal uptake of FDG in the right distal femur and residual lymphoma was taken into consideration. However, findings in the coregistered CT scan were consistent with nonossfiying fibroma, a common benign skeletal lesion. Combined PET/CT imaging can be helpful to identify benign bone lesions mimicking metastatic or residual disease in F-18 FDG PET as illustrated by this case.
一名12岁女孩被诊断为霍奇金淋巴瘤,并接受了传统的横断面成像进行初始分期。根据标准的儿科方案进行化疗。治疗结束时,进行了F-18 FDG PET/CT检查以评估治疗反应。扫描显示右股骨远端有局灶性FDG摄取,考虑为残留淋巴瘤。然而,同机CT扫描结果与非骨化性纤维瘤一致,这是一种常见的良性骨骼病变。如本病例所示,联合PET/CT成像有助于识别在F-18 FDG PET中模拟转移性或残留疾病的良性骨病变。