Hayes Edward B
Arboviral Diseases Branch, Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA.
Trans R Soc Trop Med Hyg. 2007 Oct;101(10):967-71. doi: 10.1016/j.trstmh.2007.06.013. Epub 2007 Jul 31.
Acute viscerotropic disease following yellow fever vaccination (YEL-AVD) is a rare but serious complication of vaccination with 17D yellow fever vaccine. This paper reviews the existing literature regarding YEL-AVD and discusses possible etiologic mechanisms. A greater understanding of this condition is essential to assuring safe and effective prevention of yellow fever and vaccination against other arboviral diseases for which 17D-based vaccines are being developed.
黄热病疫苗接种后急性嗜内脏性疾病(YEL-AVD)是接种17D黄热疫苗后一种罕见但严重的并发症。本文回顾了关于YEL-AVD的现有文献,并讨论了可能的病因机制。更深入地了解这种情况对于确保安全有效地预防黄热病以及研发基于17D疫苗的其他虫媒病毒疾病疫苗至关重要。