Avetisov S E, Safonova T N, Markosian A G, Kharlap S I, Kikhvantseva V G
Vestn Oftalmol. 2007 May-Jun;123(3):30-6.
The paper presents the results of three-dimensional combined tear ultrasound analysis in various diseases accompanied by the dry eye syndrome. Sixty-five patients with clinical manifestations of the dry eye syndrome were examined. Of them, there were 20 patients with Sjogren's syndrome and disease, 25 with dry eye syndrome of unknown genesis, 5 with lachrymal gland tumorous lesion, 5 with cystic lacrimal gland changes (dacryops), and 10 persons above 65 years of age (a risk group). In each of the study group the study determined the mean sizes of a ultrasound section of the lacrimal gland, its mean volume, and densitometric indices, such as density and vasculogenicity index, as well as the mean values of hemodynamic parameters in the lacrimal artery. The characteristic echographic signs of lacrimal gland structural changes and vascularization are described in Sjogren's disease and syndrome, dry eye syndrome of unknown genesis, dacryops, neoplastic processes involving the lacrimal gland. The proposed algorithm of lacrimal gland ultrasound study can enhance the accuracy and validity of results of the differential diagnosis of various lacrimal gland diseases with the clinical manifestations of the dry eye syndrome. The findings may be further used for the monitoring and detection of three-dimensional and structural changes in the lacrimal gland, which result from various pathological processes with the clinical manifestations of the dry eye syndrome.
本文介绍了在伴有干眼综合征的各种疾病中进行三维联合泪腺超声分析的结果。对65例有干眼综合征临床表现的患者进行了检查。其中,20例患有干燥综合征及相关疾病,25例患有病因不明的干眼综合征,5例患有泪腺肿瘤性病变,5例患有泪腺囊性改变(泪腺囊肿),还有10名65岁以上的患者(高危组)。在每个研究组中,均测定了泪腺超声切面的平均大小、平均体积、密度测量指标,如密度和血管生成指数,以及泪腺动脉血流动力学参数的平均值。文中描述了干燥综合征、病因不明的干眼综合征、泪腺囊肿、累及泪腺的肿瘤性病变中泪腺结构改变和血管化的特征性超声征象。所提出的泪腺超声研究算法可提高对伴有干眼综合征临床表现的各种泪腺疾病进行鉴别诊断结果的准确性和有效性。这些发现可能进一步用于监测和检测由伴有干眼综合征临床表现的各种病理过程导致的泪腺三维及结构变化。