Lannoo L, Smets S, Steenkiste E, Delforge M, Moerman P, Stroobants S, Knockaert D, Amant F
Division of Gynaecologic Oncology, Department of Obstetrics and Gynaecology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Belgium.
Acta Clin Belg. 2007 May-Jun;62(3):187-90. doi: 10.1179/acb.2007.031.
Non-Hodgkin's lymphoma (NHL) is a common cause of Fever of Unknown Origin (FUO) but the presentation as a gynaecologic malignancy is exceedingly rare. To our knowledge, this represents the first report of an intravascular large B-cell lymphoma of the uterus presenting with fever of unknown origin. After a standard clinical work-up for FUO, the endometrial curettage directed by the finding of a localized fluoro-deoxyglucose Positron Emission Tomography (FDG-PET) hot spot in the pelvic area, yielded material revealing an intr avascular B-cell lymphoma. A total abdominal hysterectomy confirmed the presence of an intravascular large B-cell lymphoma in the lumina of small blood vessels of the uterus.
非霍奇金淋巴瘤(NHL)是不明原因发热(FUO)的常见病因,但表现为妇科恶性肿瘤极为罕见。据我们所知,这是首例子宫血管内大B细胞淋巴瘤伴不明原因发热的报告。在对FUO进行标准临床检查后,根据盆腔局部氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)热点的发现进行子宫内膜刮除术,所获材料显示为血管内B细胞淋巴瘤。全腹子宫切除术证实子宫小血管腔内存在血管内大B细胞淋巴瘤。