Osaka Mariko, Komori Mie, Morishita Masanao, Osaka Naoyuki
Department of Psychology, Osaka University of Foreign Studies, Osaka, Japan.
Cogn Affect Behav Neurosci. 2007 Jun;7(2):130-9. doi: 10.3758/cabn.7.2.130.
Using fMRI, we investigated neural substrates for focusing attention in working memory. To explore this focusing effect, two kinds of reading span test (RST), focused and nonfocused, were performed. In the focused RST (F-RST), the target word to be maintained was the focus word in the sentence. In the nonfocused RST (NF-RST), the target word was not the focus word in the sentence. In both RST conditions, significant activations were found in three main regions: left dorsolateral prefrontal cortex (DLPFC), anterior cingulate cortex (ACC), and left superior parietal lobule (SPL). In addition, fMRI signal changes increased in the left SPL in the NF-RST condition. These findings suggest that the neural substrates of focusing attention are based on SPL and ACC-DLPFC networks. Furthermore, there were group differences in the focusing effect between high-span and low-span subjects: High-span subjects showed focusing effects (supported by SPL control) greater than those of low-span subjects.
我们使用功能磁共振成像(fMRI)研究了工作记忆中集中注意力的神经基础。为了探究这种集中效应,我们进行了两种阅读广度测试(RST),即集中式和非集中式。在集中式RST(F-RST)中,要记忆的目标词是句子中的重点词。在非集中式RST(NF-RST)中,目标词不是句子中的重点词。在两种RST条件下,均在三个主要区域发现了显著激活:左侧背外侧前额叶皮层(DLPFC)、前扣带回皮层(ACC)和左侧顶上小叶(SPL)。此外,在NF-RST条件下,左侧SPL的fMRI信号变化增加。这些发现表明,集中注意力的神经基础基于SPL和ACC-DLPFC网络。此外,高广度和低广度受试者在集中效应上存在组间差异:高广度受试者表现出的集中效应(由SPL控制支持)大于低广度受试者。