Xu Zuo-jun, Ding Ke, Huang Hui, Sun Tie-ying, Ke Hui-xing, Tong Zhao-hui, Wei Tian-ni, Peng Kun, Yao Bin, Li Feng-xian, Liu Jian-hua
Department of Respiratory Medicine, Peking Union Medical College, Peking Union Medical Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Jie He He Hu Xi Za Zhi. 2007 Jun;30(6):442-6.
To assess physicians' awareness and use of guidelines for community-acquired pneumonia (CAP) published by Chinese Society of Respiratory Diseases (CSRD) and American Thoracic Society (ATS), and to investigate influences of the guidelines on the prognosis of patients with CAP.
A total of 210 self-completion questionnaires about CAP guidelines were received from doctors of six hospitals in Beijing. In addition, 490 serial cases of CAP collected from these hospitals admitted from January 2002 to December 2003 were retrospectively analyzed.
Most doctors had limited knowledge about atypical pathogens. For pulmonary physicians, only 46% (97/210) reported using the CSRD guideline. 82.4% of the doctors preferred to give initial empiric antibiotic therapy according to the patients' conditions. 79.5% (167/210) of the doctors ordered examination of the pathogens routinely and 84.3% (177/210) of them admitted its usefulness for choosing antibiotics. 84.5% (414/490) of the patients responded well to the initial empiric treatment. Patients who were treated according to the guidelines of CSRD and ATS were 229 cases and 131 cases respectively. There was no significant difference in the prognosis between patients who were treated according to the guideline and those who were not. There was no significant difference in the prognosis between cases with definite pathogens and cases without.
The results indicate low levels of awareness and use of guidelines for the management of CAP. Fewer than half of the patients were treated according to the guidelines. However, the treatments were effective in most of the patients, and there was no significant difference in the prognosis between patients who were treated according to the guideline and those who were not, because broad-spectrum antibiotics were overused. More effective guideline implementation strategies are needed to encourage compliance with practice guidelines for the management of CAP.
评估医生对中国呼吸病学会(CSRD)和美国胸科学会(ATS)发布的社区获得性肺炎(CAP)指南的知晓情况及应用情况,并调查指南对CAP患者预后的影响。
从北京六家医院的医生处共收到210份关于CAP指南的自填式问卷。此外,对2002年1月至2003年12月从这些医院收治的490例CAP连续病例进行回顾性分析。
大多数医生对非典型病原体的了解有限。对于肺科医生,只有46%(97/210)报告使用CSRD指南。82.4%的医生倾向于根据患者情况给予初始经验性抗生素治疗。79.5%(167/210)的医生常规进行病原体检查,其中84.3%(177/210)承认其对选择抗生素有用。84.5%(414/490)的患者对初始经验性治疗反应良好。按照CSRD和ATS指南治疗的患者分别为229例和131例。遵循指南治疗的患者与未遵循指南治疗的患者在预后方面无显著差异。有明确病原体的病例与无明确病原体的病例在预后方面无显著差异。
结果表明对CAP管理指南的知晓和应用水平较低。不到一半的患者按照指南接受治疗。然而,大多数患者的治疗是有效的,遵循指南治疗的患者与未遵循指南治疗的患者在预后方面无显著差异,因为广谱抗生素被过度使用。需要更有效的指南实施策略来鼓励遵循CAP管理的实践指南。