Benlyazid A, Sarini J, Marques B, Garrido-Stowhas I, Delord J-P, Zerdoud S, Rives M
Département de chirurgie, institut Claudius-Regaud, 20-24, rue du Pont-Saint-Pierre, 31052 Toulouse cedex, France.
Ann Otolaryngol Chir Cervicofac. 2007 Dec;124(6):285-91. doi: 10.1016/j.aorl.2006.06.001.
To evaluate the neck control after prior surgical management of patients with squamous cell carcinoma of the oral cavity and to quantify the ratio of patients among whom neck dissection did not have a real therapeutic value. To discuss the usefulness of the sentinel node biopsy in this group of patients.
Retrospective analysis of patients with epidermoid carcinoma of the oral cavity who had systematically a neck dissection.
Thirty-nine files of patients have been processed. We found 45% patients classified pN0 (among whom about one half where classified pT4). With a mean follow-up of 19 months, we did not find any cervical lymph node relapse. Five patients died (13.5%) without any cervical disease.
The systematic cervical lymph node dissection remains the most effective means to obtain the neck control of squamous cell cancers of the oral cavity. It however was applied without therapeutic value for 45% of the patients of this series. The validation of the sentinel node concept as a method of cervical staging should make it possible to avoid this surgical procedure in more than one third of the cases.
评估口腔鳞状细胞癌患者先前手术治疗后的颈部控制情况,并量化颈部清扫术对其无实际治疗价值的患者比例。探讨前哨淋巴结活检在该组患者中的实用性。
对系统性接受颈部清扫术的口腔表皮样癌患者进行回顾性分析。
已处理39例患者的病历。我们发现45%的患者分类为pN0(其中约一半分类为pT4)。平均随访19个月,未发现任何颈部淋巴结复发。5例患者(13.5%)无任何颈部疾病死亡。
系统性颈部淋巴结清扫术仍然是实现口腔鳞状细胞癌颈部控制的最有效手段。然而,在本系列45%的患者中,该手术并无治疗价值。前哨淋巴结概念作为一种颈部分期方法的验证,应能使超过三分之一的病例避免该手术。