重组凝血因子VIIa在一名患有凝血病和硬膜下血肿的早产儿中的应用。

Use of recombinant factor VIIa in a preterm infant with coagulopathy and subdural hematoma.

作者信息

Altuncu Emel, Berrak Su, Bilgen Hülya, Yurdakul Ziya, Canpolat Cengiz, Ozek Eren

机构信息

Department of Pediatrics, Divisions of Neonatology and Hematology, School of Medicine, Marmara University, Istanbul, Turkey.

出版信息

J Matern Fetal Neonatal Med. 2007 Aug;20(8):627-9. doi: 10.1080/14767050701411935.

DOI:10.1080/14767050701411935

PMID:17674281

Abstract

Activated recombinant factor VIIa was administered to a preterm infant with bleeding diasthesis and a huge subdural hematoma that could not be controlled by the blood products. The coagulation tests were normalized the following day. Recombinant factor VIIa can be a choice in selected cases with intractable bleedings unesponsive to conventional replacement therapy.

摘要

活化重组凝血因子VIIa被用于治疗一名患有出血性素质且有巨大硬膜下血肿的早产儿，该血肿无法通过血液制品得到控制。第二天凝血试验恢复正常。重组凝血因子VIIa可作为对传统替代疗法无反应的难治性出血特定病例的一种选择。