Louie Janice K, Schnurr David P, Pan Chao-Yang, Kiang David, Carter Connie, Tougaw Sandra, Ventura Jean, Norman Agnes, Belmusto Vivian, Rosenberg Jon, Trochet Glennah
California Department of Health Services, Richmond, CA 94804, USA.
J Infect Dis. 2007 Sep 1;196(5):705-8. doi: 10.1086/519846. Epub 2007 Jul 13.
Human metapneumovirus (hMPV), a recently discovered paramyxovirus, is thought to be primarily a winter-spring pathogen affecting young children with a clinical presentation similar to that of respiratory syncytial virus. In June-July 2006, a respiratory outbreak in a long-term-care facility was reported to the local health department and investigated. Surveillance identified 26 residents and 13 staff with acute respiratory illness; 8 residents (31%) developed radiographically confirmed pneumonia, and 2 (5%) were hospitalized. Five of 14 respiratory specimens were positive by polymerase chain reaction assay for hMPV; sequencing identified genotype A. In institutionalized elderly persons, hMPV may be an important cause of respiratory outbreaks year-round.
人偏肺病毒（hMPV）是一种最近发现的副粘病毒，被认为主要是一种冬春季节的病原体，可感染幼儿，临床表现与呼吸道合胞病毒相似。2006年6月至7月，一家长期护理机构发生呼吸道疾病暴发并报告给了当地卫生部门进行调查。监测发现26名居民和13名工作人员患有急性呼吸道疾病；8名居民（31%）经影像学检查确诊为肺炎，2名（5%）住院治疗。14份呼吸道标本中有5份经聚合酶链反应检测hMPV呈阳性；测序鉴定为A基因型。在机构化的老年人中，hMPV可能是全年呼吸道疾病暴发的一个重要原因。
