Golik Tali, Reif Shimon
Pediatric Department A', "DANA" Children's Hospital, Tel Aviv Sourasky Medical Center.
Harefuah. 2007 May;146(5):335-6, 408.
Sickle cell anemia results from a genetic defect that causes a structural change in the beta-chain hemoglobin. This change causes chronic anemia. In Israel, sickle cell disease primarily affects Arab communities. Recently, immigration from Africa exposed us to sickle cell disease in this population. Three cases are presented with a variety of symptoms of sickle cell disease in this population. Awareness of this disease and its clinical presentations will prompt early diagnosis and treatment that can help these patients to avoid further complications.
镰状细胞贫血是由一种导致β链血红蛋白结构改变的基因缺陷引起的。这种改变会导致慢性贫血。在以色列，镰状细胞病主要影响阿拉伯社区。最近，来自非洲的移民使我们接触到了这一人群中的镰状细胞病。本文介绍了该人群中三例出现各种镰状细胞病症状的病例。了解这种疾病及其临床表现将促使早期诊断和治疗，从而帮助这些患者避免进一步的并发症。
