[Level of plasma fibronectin and its biological activity in patients with ovarian cancer].

Plasma level of fibronectin and its biological activity were assessed in 33 females suffering ovarian cancer; 13 cases had stage I or II disease whereas 20-stage III or IV tumors. Fibronectin level, as measured by immunoelectrophoresis, proved normal. This was accompanied by a statistically significant (p less than 0.05) rise in gelatin--binding activity of the glycoprotein in patients with stage I-II cancer which accounted for an increased value registered for the entire group studied. However, no such rise was observed in cases of stage III and IV disease.