Song X H, Ding L W, Wen H
Department of Orthopaedics, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Province, China.
Postgrad Med J. 2007 Aug;83(982):536-42. doi: 10.1136/pgmj.2007.057166.
Bone hydatid disease lacks a typical clinical appearance and image characteristics on x ray or CT are similar to those of tuberculosis, metastases and giant cell tumour or bone cysts. However, MRI does show distinctive diagnostic features of bone hydatid disease, especially in the spine. Until recently, treatment of osseous hydatid disease has been entirely surgical. Effective chemotherapy using benzimidazoles, particularly mebendazole, albendazole and combination treatments, has now been achieved in experimental studies and clinical practice. However, most of these drugs are still in the experimental stage or are in the early stages of clinical use.
骨包虫病缺乏典型的临床表现,其X线或CT图像特征与肺结核、骨转移瘤、骨巨细胞瘤或骨囊肿相似。然而,MRI确实显示出骨包虫病独特的诊断特征,尤其是在脊柱部位。直到最近,骨包虫病的治疗一直完全依靠手术。目前,在实验研究和临床实践中,使用苯并咪唑类药物,特别是甲苯达唑、阿苯达唑及联合治疗进行有效化疗已经取得进展。然而,这些药物大多仍处于实验阶段或临床应用的早期阶段。