Degowska Małgorzata, Rydzewska Grazyna
Klinika Chorób Wewnetrznych i Gastroenterologii CSK MSWiA w Warszawie.
Pol Merkur Lekarski. 2007 May;22(131):465-8.
In most patients, acute pancreatitis (AP) is a mild self-limiting disease, however for about 20% patients with clinically severe acute pancreatitis it is a live treating disease with 30% mortality. Mortality increases in patient with sterile necrosis and especially when infection has occurred. Prevention and optimal treatment of infection in AP have become a principal therapeutic target for improving the outcome of this disease. Several controlled clinical trials, often controversial, demonstrated a significant reduction of hospital mortality. In this article, we review the current opinion of the antibiotics treatment in AP.
在大多数患者中，急性胰腺炎（AP）是一种轻度的自限性疾病，然而，约20%的临床重症急性胰腺炎患者面临着危及生命的疾病，死亡率达30%。无菌性坏死患者的死亡率会增加，尤其是发生感染时。急性胰腺炎感染的预防和优化治疗已成为改善该病预后的主要治疗目标。多项对照临床试验（结果往往存在争议）表明医院死亡率显著降低。在本文中，我们综述了急性胰腺炎抗生素治疗的当前观点。
