Bajetta Emilio, Platania Marco, Catena Laura, Bichisao Ettore, Fabbri Alessandra, Procopio Giuseppe, De Dosso Sara, Buzzoni Roberto
Unit of Medical Oncology 2, Centro di Riferimento per lo Studio e la Cura del Carcinoide e dei Tumori Neuroendocrini (CeRiCa), Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Tumori. 2007 May-Jun;93(3):323-6. doi: 10.1177/030089160709300321.
Merkel cell carcinoma is a rare and aggressive neuroendocrine skin cancer with a very low incidence in the general population. MCC seems to be common in transplant recipients and 52 cases have been reported in the literature.
This report describes a Merkel cell carcinoma which developed in a liver transplant recipient. To our knowledge, this is the second such case reported, as Merkel cell carcinoma most commonly occurs after kidney and heart transplants. The treatment approach is described and the literature on the subject is reviewed.
There is currently no consensus regarding the optimal therapeutic approach to Merkel cell carcinoma. In transplant recipients, such tumors are more common and more aggressive but their treatment does not differ from the treatment of Merkel cell carcinomas in the general population.
默克尔细胞癌是一种罕见的侵袭性神经内分泌皮肤癌，在普通人群中的发病率极低。默克尔细胞癌在移植受者中似乎较为常见，文献中已报道了52例。
本报告描述了一例发生在肝移植受者身上的默克尔细胞癌。据我们所知，这是第二例此类病例报道，因为默克尔细胞癌最常发生在肾移植和心脏移植后。文中描述了治疗方法并对该主题的文献进行了综述。
目前对于默克尔细胞癌的最佳治疗方法尚无共识。在移植受者中，此类肿瘤更为常见且更具侵袭性，但其治疗与普通人群中默克尔细胞癌的治疗并无不同。
