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用灭活西尼罗河病毒疫苗接种后五种鸟类的抗体反应。

Antibody response of five bird species after vaccination with a killed West Nile virus vaccine.

作者信息

Okeson Danelle M, Llizo Shirley Yeo, Miller Christine L, Glaser Amy L

机构信息

Center for Conservation and Research, Henry Doorly Zoo, 3701 South Tenth Street, Omaha, Nebraska 68107, USA.

出版信息

J Zoo Wildl Med. 2007 Jun;38(2):240-4. doi: 10.1638/1042-7260(2007)038[0240:AROFBS]2.0.CO;2.

Abstract

West Nile virus has been associated with numerous bird mortalities in the United States since 1999. Five avian species at three zoological parks were selected to assess the antibody response to vaccination for West Nile virus: black-footed penguins (Spheniscus demersus), little blue penguins (Eudyptula minor), American flamingos (Phoenicopterus ruber), Chilean flamingos (Phoenicopterus chilensis), and Attwater's prairie chickens (Tympanuchus cupido attwateri). All birds were vaccinated intramuscularly at least twice with a commercially available inactivated whole virus vaccine (Innovator). Significant differences in antibody titer over time were detected for black-footed penguins and both flamingo species.

摘要

自1999年以来,西尼罗河病毒在美国已导致大量鸟类死亡。选取了三个动物园的五种鸟类来评估其对西尼罗河病毒疫苗接种的抗体反应:非洲企鹅(Spheniscus demersus)、小蓝企鹅(Eudyptula minor)、美洲火烈鸟(Phoenicopterus ruber)、智利火烈鸟(Phoenicopterus chilensis)和阿特沃特草原鸡(Tympanuchus cupido attwateri)。所有鸟类均通过肌肉注射,至少两次接种市售的灭活全病毒疫苗(Innovator)。检测到非洲企鹅和两种火烈鸟的抗体滴度随时间存在显著差异。

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