Lulich J P, Osborne C A, Unger L K, Sanna J, Clinton C W, Davenport M P
Department of Small Animal Clinical Sciences College of Veterinary Medicine, University of Minnesota, St Paul 55108.
Am J Vet Res. 1991 Oct;52(10):1579-82.
Epidemiologic data were evaluated from all dogs admitted to the University of Minnesota, Veterinary Teaching Hospital (UMVTH) between June 1981 and November 1989. Of 69,890 admissions, 2,077 were Miniature Schnauzers. Uroliths were retrieved from 63 of the 2,077 Miniature Schnauzers admitted. In 20 of the 63 urolith episodes, calcium oxalate was the predominant mineral identified. By comparison, calcium oxalate uroliths were identified in only 56 of the remaining 67,813 non-Miniature Schnauzer canine admissions. The odds that uroliths from Miniature Schnauzers were composed of calcium oxalate was 11.8 times greater than for other canine breeds evaluated at the UMVTH (95% confidence interval = 6.8 to 20.1). Data also were evaluated from files of uroliths retrieved from dogs and submitted to the Minnesota Urolith Center for quantitative mineral analysis, between June 1981 and November 1989. Of 3,930 uroliths analyzed, 615 (15.6%) uroliths were obtained from Miniature Schnauzers. of the 615 uroliths, 175 (28.4%) were calcium oxalate. By comparison, only 550 (16.6%) of the remaining 3,315 from dogs of breeds other than Miniature Schnauzers were calcium oxalate. The odds that uroliths submitted for analysis were composed of calcium oxalate was 2 times greater for Miniature Schnauzers than for dogs of other breeds (95% confidence interval = 1.6 to 2.4). Calcium oxalate uroliths were retrieved more frequently in males than females. The risk for males developing calcium oxalate uroliths was greater than 3 times the risk for females in both groups of data evaluated. The mean age of all Miniature Schnauzers admitted to the UMVTH with calcium oxalate uroliths was 9 years. Calcium oxalate uroliths were not detected in Miniature Schnauzers younger than 1.7 years.
对1981年6月至1989年11月间明尼苏达大学兽医学院教学医院（UMVTH）收治的所有犬只的流行病学数据进行了评估。在69890例入院病例中，有2077只为迷你雪纳瑞犬。在收治的2077只迷你雪纳瑞犬中，有63只取出了尿石。在63例尿石病例中，有20例鉴定出草酸钙为主要矿物质。相比之下，在其余67813例非迷你雪纳瑞犬的入院病例中，仅56例鉴定出草酸钙尿石。迷你雪纳瑞犬的尿石由草酸钙组成的几率比UMVTH评估的其他犬种高11.8倍（95%置信区间=6.8至20.1）。还对1981年6月至1989年11月间从犬只取出并提交给明尼苏达尿石中心进行矿物质定量分析的尿石档案数据进行了评估。在分析的3930颗尿石中，615颗（15.6%）尿石来自迷你雪纳瑞犬。在这615颗尿石中，175颗（28.4%）为草酸钙。相比之下，在其余3315颗非迷你雪纳瑞犬种的尿石中，只有550颗（16.6%）是草酸钙。提交分析的尿石由草酸钙组成的几率，迷你雪纳瑞犬比其他犬种高2倍（95%置信区间=1.6至2.4）。草酸钙尿石在雄性犬中比雌性犬更频繁地被取出。在评估的两组数据中，雄性犬患草酸钙尿石的风险比雌性犬高3倍以上。入住UMVTH的患有草酸钙尿石的所有迷你雪纳瑞犬的平均年龄为9岁。1.7岁以下的迷你雪纳瑞犬未检测到草酸钙尿石。
