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[下肢慢性动脉缺血中微循环障碍的病理生理特征]

[Pathophysiological characteristics of microcirculatory disorders in chronic arterial ischaemia of lower limbs].

作者信息

Kozlov V I, Azizov G A

机构信息

Russian University of Friendship of Peoples, Chair of Laser Medicine, Moscow, Russia.

出版信息

Angiol Sosud Khir. 2007;13(1):17-23.

Abstract

Presented herein are the findings of studying the peculiarities of the systemic and regional haemodynamics in patients with obliterating atherosclerosis of the arteries of the lower limbs. We examined a total of 186 patients with stage I-IV chronic arterial ischaemia of the lower extremities using the following methods: computer-assisted TV microscopy of the vessels of the conjunctiva of the eyeball and of the skin of the lower limbs, laser Doppler flowmetry (LDF) and transcutaneous determination of oxygen tension. Revealed were: spastic, congestive, Presented herein are the findings of studying the peculiarities of the systemic and regional haemodynamics in patients with obliterating atherosclerosis of the arteries of the lower limbs. We examined a total of 186 patients with stage I-IV chronic arterial ischaemia of the lower extremities using the following methods: computer-assisted TV microscopy of the vessels of the conjunctiva of the eyeball and of the skin of the lower limbs, laser Doppler flowmetry (LDF) and transcutaneous determination of oxygen tension. Revealed were: spastic, congestive, spastic-atonic and stasic forms of microcirculatory disorders. It was determined that microcirculatory disorders in obliterating atherosclerosis of the lower limbs are systemic, to be revealed both in the extremities affected and in the conjunctiva of the eyeball. A pathophysiologically substantiated classification of microcirculatory disorders is proposed herein.

摘要

本文展示了对下肢动脉闭塞性动脉粥样硬化患者全身和局部血流动力学特点的研究结果。我们使用以下方法对总共186例患有I-IV期下肢慢性动脉缺血的患者进行了检查:计算机辅助电视显微镜检查眼球结膜和下肢皮肤的血管、激光多普勒血流仪(LDF)以及经皮测定氧分压。结果发现了微循环障碍的痉挛型、充血型、痉挛-无张力型和停滞型。确定下肢闭塞性动脉粥样硬化中的微循环障碍是全身性的,在受影响的肢体和眼球结膜中均可发现。本文提出了一种基于病理生理学的微循环障碍分类方法。

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