Bongiovanni Marco, Gori Andrea, Lepri Alessandro Cozzi, Antinori Andrea, de Luca Andrea, Pagano Gabriella, Chiodera Alessandro, Puoti Massimo, Monforte Antonella d'Arminio
Clinic of Infectious Diseases, San Paolo Hospital, University of Milan, Milan, Italy.
Clin Infect Dis. 2007 Sep 1;45(5):650-3. doi: 10.1086/520025. Epub 2007 Aug 1.
Recently, it was shown that cirrhotic patients without human immunodeficiency virus (HIV) infection had low CD4 cell counts and normal CD4 cell percentages, suggesting that, for HIV-infected persons, the CD4 cell percentage might be a more accurate marker of disease progression than the absolute CD4 cell count. In cirrhotic HIV-infected persons in the Italian Cohort of Antiretroviral-Naive Patients, the absolute CD4 cell count seemed to be better predictor of the risk of developing an acquired immunodeficiency syndrome-defining illness than the CD4 cell percentage.
最近的研究表明，未感染人类免疫缺陷病毒（HIV）的肝硬化患者CD4细胞计数较低，但CD4细胞百分比正常，这表明，对于HIV感染者而言，CD4细胞百分比可能比CD4细胞绝对计数更能准确反映疾病进展情况。在意大利初治抗逆转录病毒治疗患者队列中的肝硬化HIV感染者中，CD4细胞绝对计数似乎比CD4细胞百分比更能预测获得性免疫缺陷综合征界定疾病的发病风险。
