Hung J H, Ng H T, Shei K S, Pan Y P, Yen K T, Yang M J, Yang M L, Shu L P
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taiwan, Republic of China.
Fetal Diagn Ther. 1991;6(1-2):65-73. doi: 10.1159/000263626.
A Duplex Color apparatus equipped with real-time imaging and Doppler sector scanner was used to scan fetal hearts, ranging from 17 to 41 weeks gestational age. A total of 323 normal fetuses were studied. The four-chamber view was obtained in a horizontal section just above the level of the fetal diaphragm. Five variables of the Chinese fetal heart in relation to the width of the right ventricle, width of the left ventricle, ratio of right ventricle/left ventricle (RV/LV), length of the fetal heart and the cardiac volume of a four-chamber view were set against gestational age in weeks and expressed in regression equations. The ratio of RV/LV is quite constant in relation to the gestational age. The mean ranges between 0.9916 for 17 weeks gestation and 1.0045 for a term fetus. In 10 abnormal cases with congenital cardiac defects, using the 5th and the 95th percentiles of this normal data as cutoff points, the RV/LV ratio had the highest sensitivity rate of 70% (7/10) in predicting fetal cardiac anomaly. The width of the left ventricle was the second most sensitive parameter with a sensitivity of 4/10 (40%). The RV/LV ratio of a four-chamber view is a simple, time-saving screening parameter for predicting congenital cardiac defects antenatally.
使用配备实时成像和多普勒扇形扫描仪的双平面彩色设备对孕龄为17至41周的胎儿心脏进行扫描。共研究了323例正常胎儿。在胎儿膈肌水平上方的水平切面获取四腔心切面图像。将中国胎儿心脏的五个变量，即右心室宽度、左心室宽度、右心室/左心室比值（RV/LV）、胎儿心脏长度和四腔心切面的心脏容积与孕周进行对照，并以回归方程表示。RV/LV比值与孕周相当恒定。其平均值在孕17周时为0.9916，足月胎儿时为1.0045。在10例先天性心脏缺陷的异常病例中，以该正常数据的第5和第95百分位数作为截断点，RV/LV比值在预测胎儿心脏异常方面的敏感性最高，为70%（7/10）。左心室宽度是第二敏感的参数，敏感性为4/10（40%）。四腔心切面的RV/LV比值是一种简单、省时的产前预测先天性心脏缺陷的筛查参数。
