Kaan G L, Noyez L, Vincent J G, van de Wal H, Skotnicki S H, Lacquet L K
Department of Thoracic and Cardiac Surgery, University Hospital St. Radboud, Nijmegen, The Netherlands.
ASAIO Trans. 1991 Oct-Dec;37(4):559-63.
The authors began ventricular assist pumping as treatment for postcardiotomy cardiogenic shock in November 1988 with a new automated pulsatile support system, the ABIOMED BVS 5000 Bi-Ventricular Support System. Five patients (0.6% of total cardiac surgery patients) have been placed on support, four after coronary artery bypass grafting, and one after bypass grafting and mitral valve repair. All patients were refractory to pharmacologic and intraaortic balloon pump therapy. Three patients had left ventricular support and two had biventricular support. Four patients were successfully weaned, and three are long-term survivors. Duration of support ranged from 39 to 118 hours (mean, 89.4 hours). Resternotomy was performed in four patients: twice for hemostasis, once for tamponade, and once for inadequate left ventricular drainage. Three patients, two nonsurvivors and one survivor, had perioperative myocardial infarctions. No device related thromboembolic complications, hemolysis, or infection were experienced. Follow-up at more than 1 year demonstrated that all patients are in NYHA Class 1. Ventricular assist pumping with the ABIOMED BVS 5000 Bi-Ventricular Support System is an effective treatment for postcardiotomy cardiogenic shock.
1988年11月，作者开始使用一种新型自动搏动支持系统——ABIOMED BVS 5000双心室支持系统，对心脏手术后的心源性休克进行心室辅助泵治疗。5例患者（占心脏手术患者总数的0.6%）接受了支持治疗，其中4例在冠状动脉搭桥术后，1例在搭桥术和二尖瓣修复术后。所有患者对药物治疗和主动脉内球囊泵治疗均无效。3例患者接受左心室支持，2例接受双心室支持。4例患者成功撤机，3例为长期存活者。支持时间为39至118小时（平均89.4小时）。4例患者进行了再次开胸手术：2次用于止血，1次用于心包填塞，1次用于左心室引流不足。3例患者，2例死亡，1例存活，发生了围手术期心肌梗死。未出现与设备相关的血栓栓塞并发症、溶血或感染。超过1年的随访表明，所有患者的心功能均为纽约心脏协会（NYHA）Ⅰ级。使用ABIOMED BVS 5000双心室支持系统进行心室辅助泵治疗是心脏手术后心源性休克的一种有效治疗方法。
