Marenzi Giancarlo, Marana Ivana, Bartorelli Antonio
Centro Cardiologico Monzino, I.R.C.C.S., Istituto di Cardiologia, Università, Milano.
Recenti Prog Med. 2007 Jul-Aug;98(7-8):367-72.
Primary angioplasty represents the best strategy for myocardial reperfusion in ST-elevation acute myocardial infarction. However, it is associated with a high risk of developing contrast-induced nephropathy, a renal complication coupled with markedly increased morbidity and mortality rates. This paper summarizes, on the current evidence available, the clinical and prognostic relevance of renal insufficiency and contrast-induced nephropathy in acute myocardial infarction, and emphasizes new possible preventive strategies for kidney protection in this clinical setting.
直接经皮冠状动脉腔内血管成形术是ST段抬高型急性心肌梗死心肌再灌注的最佳策略。然而,它与发生造影剂肾病的高风险相关,造影剂肾病是一种肾脏并发症,会显著增加发病率和死亡率。本文根据现有证据,总结了急性心肌梗死中肾功能不全和造影剂肾病的临床及预后相关性,并强调了在这种临床情况下肾脏保护的新的可能预防策略。