低浓度环丙烷和氟烷对眼球扫视运动峰值速度的影响。

Effects of low concentrations of cyclopropane and halothane on peak velocity of saccadic eye movements.

作者信息

Yoshizumi J, Marshall R W, Vickers M D

机构信息

Department of Anaesthetics, University of Wales College of Medicine, Heath Park, Cardiff.

出版信息

Br J Anaesth. 1991 Dec;67(6):735-40. doi: 10.1093/bja/67.6.735.

DOI:10.1093/bja/67.6.735

PMID:1768543

Abstract

We have investigated the effect of 4.7 and 8.8% MAC of cyclopropane, and 5.3 and 9.3% MAC of halothane on the peak velocity of saccadic eye movements (PSV) in six healthy volunteers. Both concentrations of cyclopropane and halothane significantly depressed PSV (P less than 0.01) compared with air, in a dose-related fashion. Halothane depressed PSV significantly more than cyclopropane (P less than 0.05). PSV returned to baseline within 5 min after discontinuation of the agents. There was no significant difference between cyclopropane, halothane and air in subjective assessment of sedation.

摘要

我们研究了4.7%和8.8%最低肺泡有效浓度（MAC）的环丙烷，以及5.3%和9.3% MAC的氟烷对6名健康志愿者眼球扫视运动峰值速度（PSV）的影响。与空气相比，环丙烷和氟烷的这两种浓度均以剂量相关的方式显著降低了PSV（P<0.01）。氟烷对PSV的降低作用明显大于环丙烷（P<0.05）。停用这些药物后5分钟内，PSV恢复到基线水平。在镇静的主观评估方面，环丙烷、氟烷和空气之间没有显著差异。