Song Ying-na, Zhu Lan, Lang Jing-he
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi. 2007 May 8;87(17):1184-6.
To investigate the clinical characteristics and the rule of recurrence of mature ovarian teratoma.
The clinical data of 20 patients with recurrent mature ovarian teratoma treated 1965 approximately 2002 was analyzed retrospectively and compared with the data of 40 patients without recurrence who were randomly selected at the ratio of 1 patient with recurrence to 2 patients without recurrence and who underwent surgical treatment in the same operation dates as the corresponding patients with recurrence.
The overall recurrence rate after The patients with recurrence was (26 +/- 7) years old on average at the onset of recurrence, significantly younger than those without recurrence [(30 +/- 6 yearly old, P < 0.05). There were no significant differences in gravidity, parity, and the cyst size, manner of surgery, and rupture during operation between the 2 groups (all P > 0.05). The incidence rates of bilateral or multilocular cysts in the patients with recurrence were significantly higher than those of the patients without recurrence (P < 0.05 or P < 0.01). The overall recurrence rate after conservative treatment was 2.5%. The mean period of recurrence was 8 +/- 7 years.
Younger patients and patients bilateral or multiple dermoid cysts should be followed up closely. Laparoscopy is the best treatment choice for mature ovarian teratoma. Biopsy of the contralateral ovary is not recommended regularly in surgery.
探讨成熟性卵巢畸胎瘤的临床特征及复发规律。
回顾性分析1965年至2002年期间接受治疗的20例复发性成熟性卵巢畸胎瘤患者的临床资料，并与随机选取的40例未复发患者的数据进行比较，选取比例为1例复发患者对应2例未复发患者，且两组患者在相同手术日期接受手术治疗。
复发患者复发时平均年龄为（26±7）岁，显著低于未复发患者[（30±6）岁，P<0.05]。两组患者在妊娠次数、产次、囊肿大小、手术方式及术中破裂情况方面差异均无统计学意义（均P>0.05）。复发患者双侧或多房囊肿的发生率显著高于未复发患者（P<0.05或P<0.01）。保守治疗后的总复发率为2.5%。平均复发时间为8±7年。
年轻患者以及双侧或多发皮样囊肿患者应密切随访。腹腔镜手术是成熟性卵巢畸胎瘤的最佳治疗选择。手术中不建议常规对侧卵巢活检。
