Jovanović Ivan, Pavlović Aleksandra, Popović Dragan, Pavlov Maja
Clinical Center of Serbia, Clinic of Gastroenterology and Hepatology, Belgrade, Serbia.
Vojnosanit Pregl. 2007 Jun;64(6):417-20. doi: 10.2298/vsp0706417j.
Although uncommon, giant submucosal colon lipomas merit attention as they are often presented with dramatic clinical features such as bleeding, acute bowel obstruction, perforation and sometimes may be mistaken for malignancy. There is a great debate in the literature as to how to treat them.
A patient, 67-year old, was admitted to the Clinic due to a constipation over the last several months, increasing abdominal pain mainly localized in the left lower quadrant accompanied by nausea, vomiting and abdominal distension. Physical examination was unremarkable and the results of the detailed laboratory tests and carcinoembryonic antigen remained within normal limits. Colonoscopy revealed a large 10 cm long, and 4 to 5 cm in diameter, mobile lesion in his sigmoid colon. Conventional endoscopic ultrasound revealed 5 cm hyperechoic lesion of the colonic wall. Twenty MHz mini-probe examination showed that lesion was limited to the submucosa. Since polyp appeared too large for a single transaction, it was removed piecemeal. Once the largest portion of the polyp has been resected, it was relatively easy to place the opened snare loop around portions of the residual polyp. Endoscopic resection was carried out safely without complications. Histological examination revealed the common typical histological features of lipoma elsewhere. The patient remained stable and eventually discharged home. Four weeks later he suffered no recurrent symptoms.
Colonic lipomas can be endoscopically removed safely eliminating unnecessary surgery.
尽管巨大的结肠黏膜下脂肪瘤并不常见,但因其常伴有出血、急性肠梗阻、穿孔等显著临床特征,有时还可能被误诊为恶性肿瘤,故而值得关注。关于如何治疗此类疾病,文献中存在诸多争议。
一名67岁患者因过去数月便秘、主要位于左下腹的腹痛加剧,并伴有恶心、呕吐和腹胀而入住诊所。体格检查无异常,详细实验室检查及癌胚抗原结果均在正常范围内。结肠镜检查发现其乙状结肠有一个长10厘米、直径4至5厘米的可移动病变。传统内镜超声显示结肠壁有一个5厘米的高回声病变。20兆赫微型探头检查显示病变局限于黏膜下层。由于息肉过大无法一次性切除,遂分块切除。切除息肉最大部分后,将打开的圈套器套住残留息肉部分相对容易。内镜切除安全完成,无并发症。组织学检查显示为其他部位脂肪瘤常见的典型组织学特征。患者病情稳定,最终出院。四周后未出现复发症状。
结肠脂肪瘤可通过内镜安全切除,避免不必要的手术。