Marra B
Divisione di Chirurgia Generale, Regione Campania-USL n. 44, Ospedale Cardinale Ascalesi, Napoli.
Minerva Chir. 1993 Sep 30;48(18):1035-9.
Lipomas occur through the intestinal tract, from the hypopharynx to the rectum, the colon having the highest incidence, where lipomata are the commonest benign neoplasm after adenomata. Nevertheless they are uncommon. CASE REPORT. 1) A 68-year-old man presented as an emergency with abdominal pain associated with bowel obstruction. He had a 2 to 3 month history of intermittent right-sided abdominal pain, constipation spontaneously resolved. At laparotomy there was a mass of the transverse colon, next hepatic flexure. A right hemicolectomy was performed. The patient made an uneventful recovery. Histologic examination showed a lipoma of the submucosal plane. 2) A 65-year-old man presented as an emergency with lower abdominal pain associated with a prolapsed rectal polyp. He had 1 month history of passing fresh blood per rectum. Ap ast colonoscopy revealed a large polypoid lesion in the descending colon. Transanal examination revealed a polypoid lesion with a maximum diameter of 4 cm, acting as an intussuseptum. Transanal polypectomy was performed. At laparotomy there was an intussuseptum of the descending colon into the rectum: a left hemicolectomy was performed. Histology showed the polyp to be a submucosal lipoma. DISCUSSION. Lipomas are the most common benign nonepithelial tumors of the colon. Lipomata of the large bowel are reported as incidental findings in 0.3-0.5% of cases in large series of autopsies. In the wall of the intestine most lie in the submucosal plane, less frequently they are found in the subserosal plane. The commonest site for symptomatic solitary large bowel lipoma is the ascending colon, including the caecum, followed by the transverse colon, including both hepatic and splenic flexure, descending colon, sigmoid colon and rectum. The peak incidence for lipomata of the large bowel is in fifth-sixth decade. Colonic lipomas are generally asymptomatic but occasionally patients may have intermittent crampy abdominal pain secondary to intussusception of a pedunculated lipoma or with intermittent fresh rectal bleeding. On barium enema lipomas appear circular, ovoid, well demarcated, and smooth. A barium enema showing a relatively radiolucent mass, caused by the radiolucency of fat, is suggestive of a lipoma. The water enema, with water as the contrast agent, accentuates the difference in density between a lipoma and surrounding tissues. Another characteristic feature of lipomas on barium enema is said to be their fluctuation in size and shape during the study: "squeeze sign". Lipomas of the large bowel can be seen, however, by colonoscopy. On computerized tomography scan the lipoma has a uniform appearance and density. In expert hands pedunculated and sessile lesions can be removed endoscopically, but often large bowel lipomata are treated on the basis of a presumptive malignant diagnosis with exploratory laparotomy. CONCLUSION. Colonic lipomas, although unusual, continue to present difficulties in the preoperative differentiation between malignant and benign colonic neoplasm. Two cases of colonic lipomas are reported.
脂肪瘤可发生于整个肠道,从下咽至直肠,其中结肠发病率最高,脂肪瘤是继腺瘤之后最常见的良性肿瘤。然而,它们并不常见。病例报告:1)一名68岁男性因腹痛伴肠梗阻急诊入院。他有2至3个月间歇性右侧腹痛病史,便秘可自行缓解。剖腹探查时发现横结肠有一肿块,紧邻肝曲。行右半结肠切除术。患者恢复顺利。组织学检查显示为黏膜下层脂肪瘤。2)一名65岁男性因下腹痛伴直肠息肉脱垂急诊入院。他有1个月直肠便血病史。既往结肠镜检查显示降结肠有一巨大息肉样病变。经肛门检查发现一最大直径4 cm的息肉样病变,为套叠肠套头。行经肛门息肉切除术。剖腹探查时发现降结肠套入直肠形成肠套叠:行左半结肠切除术。组织学检查显示息肉为黏膜下层脂肪瘤。讨论:脂肪瘤是结肠最常见的良性非上皮性肿瘤。在大量尸检系列中,大肠脂肪瘤的偶然发现率为0.3% - 0.5%。在肠壁中,大多数脂肪瘤位于黏膜下层,较少见于浆膜下层。有症状的孤立性大肠脂肪瘤最常见的部位是升结肠,包括盲肠,其次是横结肠,包括肝曲和脾曲、降结肠、乙状结肠和直肠。大肠脂肪瘤的发病高峰在五六十岁。结肠脂肪瘤通常无症状,但偶尔患者可能因带蒂脂肪瘤套叠继发间歇性痉挛性腹痛或伴有间歇性新鲜直肠出血。在钡剂灌肠检查中,脂肪瘤表现为圆形、椭圆形,边界清晰且光滑。钡剂灌肠显示相对透光的肿块,因脂肪的透光性所致,提示脂肪瘤。以水为造影剂的水灌肠可增强脂肪瘤与周围组织密度的差异。钡剂灌肠检查中脂肪瘤的另一个特征性表现据说是在检查过程中其大小和形状会波动:“挤压征”。然而,大肠脂肪瘤可通过结肠镜检查发现。在计算机断层扫描中,脂肪瘤外观和密度均匀。在专家手中,带蒂和无蒂病变可通过内镜切除,但大肠脂肪瘤通常基于疑似恶性诊断而行剖腹探查术。结论:结肠脂肪瘤虽然不常见,但在术前鉴别结肠良恶性肿瘤方面仍存在困难。本文报告两例结肠脂肪瘤。