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肺移植术中的经食管超声心动图检查

Transesophageal echocardiography during lung transplantation.

作者信息

Serra E, Feltracco P, Barbieri S, Forti A, Ori C

机构信息

Department of Pharmacology and Anesthesia, University Hospital of Padova, Padova, Italy.

出版信息

Transplant Proc. 2007 Jul-Aug;39(6):1981-2. doi: 10.1016/j.transproceed.2007.05.004.

Abstract

Transesophageal echocardiography (TEE) is a semi-invasive monitoring technique increasingly used in cardiac surgery and in major noncardiac surgery for patients with known or supposed cardiac or coronary problems. During lung transplantation (LTx), the close interrelation between heart and lung function makes TEE an invaluable tool for instantly monitoring the physiopathological situation in the subsequent steps of the intervention. In patients scheduled for LTx, induction of anesthesia could be a dangerous moment with the possibility of cardiogenic shock if pulmonary hypertension (PH) exists; pneumatic tamponade is also possible in patients with emphysema caused by alpha(1)-antitrypsin deficiency, with subsequent cardiac insufficiency. One-lung ventilation is a critical phase during LTx; hypoxemia resulting from ventilation of a diseased dependent lung could impair heart oxygenation, particularly if tachycardia is present. Clamping of the pulmonary artery before pneumonectomy could exacerbate cardiac afterload, especially in patients with previous PH. High transmural pressure, linked with low systemic pressure, makes right ventricle (RV) perfusion pressure inadequate. Hypoxemia and PH are the most frequent causes of intraoperative RV decompensation. In this special setting, TEE is irreplaceable in informing the anesthesiologist about the correct time for extracorporeal oxygenation. Lung reperfusion brings with it the possibility of coronary gaseous embolism, easily detected with TEE. After LTx, TEE can be used to detect strictures, thrombi, or permeability of pulmonary venous anastomoses. To summarize, intraoperative TEE during LTx contributes to the immediate recognition of critical events and allows for rapid therapeutic interventions.

摘要

经食管超声心动图(TEE)是一种半侵入性监测技术,越来越多地用于心脏手术以及患有已知或疑似心脏或冠状动脉问题的患者的大型非心脏手术。在肺移植(LTx)过程中,心脏和肺功能之间的密切相互关系使TEE成为在干预后续步骤中即时监测生理病理状况的宝贵工具。对于计划进行LTx的患者,如果存在肺动脉高压(PH),麻醉诱导可能是一个危险时刻,有可能发生心源性休克;对于由α1抗胰蛋白酶缺乏引起的肺气肿患者,也可能发生气胸,继而导致心脏功能不全。单肺通气是LTx过程中的关键阶段;患病依赖肺通气导致的低氧血症可能会损害心脏氧合,特别是在存在心动过速的情况下。肺叶切除术前夹闭肺动脉可能会加重心脏后负荷,尤其是既往有PH的患者。高跨壁压与低体循环压力相关,会使右心室(RV)灌注压力不足。低氧血症和PH是术中RV失代偿最常见的原因。在这种特殊情况下,TEE在告知麻醉医生体外氧合的正确时机方面是不可替代的。肺再灌注会带来冠状动脉气体栓塞的可能性,TEE很容易检测到。LTx术后,TEE可用于检测肺静脉吻合口的狭窄、血栓或通透性。总之,LTx术中TEE有助于立即识别关键事件并允许进行快速治疗干预。

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