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软组织恶性孤立性纤维性肿瘤:一项细胞遗传学研究

Malignant solitary fibrous tumor of the soft tissue: a cytogenetic study.

作者信息

Hoshino Makiko, Ogose Akira, Kawashima Hiroyuki, Kudo Naoko, Hotta Tetsuo, Umezu Hajime, Tohyama Tsuyoshi, Nakade Kazuhiro, Beppu Hiroki, Endo Naoto

机构信息

Division of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University Hospital, Asahimachi 1-751, Niigata 951-8510, Japan.

出版信息

Cancer Genet Cytogenet. 2007 Aug;177(1):55-8. doi: 10.1016/j.cancergencyto.2007.04.016.

DOI:10.1016/j.cancergencyto.2007.04.016
PMID:17693192
Abstract

We report on a case of a solitary fibrous tumor that developed in the thigh of an 82-year-old woman. The tumor was composed of areas of high-grade sarcoma and typical solitary fibrous tumor. Its karyotype was: 70,XXX,+X[4],+1[2],add(1)(p36)[4],add(1)[2],+2[4],-3[4],+6[4],add(6)(p11)x2[4],+7[4],+9[3],-11[4],-12[4],-13[4],add(13)(p11)x2[4],-14[4],+15[4],-16[3],-17[4],-19[4],+20,[4],+21[4],+22[2],+mar1x2[4][cp4].

摘要

我们报告了一例发生在一名82岁女性大腿的孤立性纤维瘤病例。该肿瘤由高级别肉瘤区域和典型的孤立性纤维瘤组成。其核型为:70,XXX,+X[4],+1[2],add(1)(p36)[4],add(1)[2],+2[4],-3[4],+6[4],add(6)(p11)x2[4],+7[4],+9[3],-11[4],-12[4],-13[4],add(13)(p11)x2[4],-14[4],+15[4],-16[3],-17[4],-19[4],+20,[4],+21[4],+22[2],+mar1x2[4][cp4] 。

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引用本文的文献

1
Solitary fibrous tumor of soft tissue: a case report and immunohistochemical study.软组织孤立性纤维性肿瘤:一例报告及免疫组织化学研究
Med Mol Morphol. 2010 Mar;43(1):60-4. doi: 10.1007/s00795-009-0451-1. Epub 2010 Mar 26.
2
Lack of a common or characteristic cytogenetic anomaly in solitary fibrous tumor.孤立性纤维瘤中缺乏常见或特征性的细胞遗传学异常。
Cancer Genet Cytogenet. 2008 Feb;181(1):60-4. doi: 10.1016/j.cancergencyto.2007.11.005.