Cherry Robert A, King Tonya S, Carney Daniel E, Bryant Patrick, Cooney Robert N
Department of Surgery, Milton S. Hershey Medical Center, Hershey, Pennsylvania 17033, USA.
J Trauma. 2007 Aug;63(2):326-30. doi: 10.1097/TA.0b013e31811eaad1.
Trauma centers use injury mechanism, physiology, and anatomic criteria to determine the extent of trauma team activation (TTA). We examined whether physiologic variables in our three-tier TTA system stratified patients appropriately by injury severity and mortality.
The trauma registry at our Level I trauma center was retrospectively reviewed for full (level 1 or L1), partial (level 2 or L2), and limited (level 3) adult TTA. Data were collected on age, injury severity score (ISS), hospital length of stay, systolic blood pressure (SBP), heart rate, respiratory rate (RR), Glasgow coma score (GCS), and intubation status. Penetrating injuries, traumatic arrests, and interfacility transfers were excluded. Data are median (25%75%). Statistical analysis included hazard ratios (HzR), Kruskal-Wallis, chi, and survival analyses. The p value overall was <0.05, and pair wise was <0.05 versus L1.
There were 494 adult TTAs for blunt injury from the scene out of 1,969 admissions. Variables associated with mortality (HzR; 95% confidence interval) by univariate analysis include SBP <90 (9.4; 4.2, 21.2), RR >29 or <10 (17.8; 4.8, 66.0), intubation status (4.5; 2.3, 8.9), and GCS <8 (9.7; 4.8, 19.9). When combined in a multivariate model to evaluate multiple predictors simultaneously, SBP <90 and GCS <8 appear to be the strongest predictors of mortality (RR and intubation were not significant in the presence of SBP and GCS). The three-tier system identified patients with increased ISS and early (< or =4 weeks) mortality risk. There was a statistically significant difference in survival between L1 and L2 at 38 days, but not for >38 days (p = 0.739).
TTA criteria selected patients with greater ISS and early mortality, but impact on long-term survival may not be appreciated. Full TTA criteria for blunt injury may be limited to GCS <8, SBP <90, RR >29 or <10, and intubation status.
创伤中心利用损伤机制、生理学和解剖学标准来确定创伤团队启动(TTA)的程度。我们研究了在我们的三级TTA系统中,生理变量是否能根据损伤严重程度和死亡率对患者进行适当分层。
对我们一级创伤中心的创伤登记资料进行回顾性分析,纳入完全(1级或L1)、部分(2级或L2)和有限(3级)成人TTA病例。收集患者的年龄、损伤严重程度评分(ISS)、住院时间、收缩压(SBP)、心率、呼吸频率(RR)、格拉斯哥昏迷评分(GCS)和插管状态等数据。排除穿透伤、创伤性心跳骤停和机构间转运患者。数据以中位数(25%~75%)表示。统计分析包括风险比(HzR)、Kruskal-Wallis检验、卡方检验和生存分析。总体p值<0.05,与L1组相比的两两比较p值<0.05。
在1969例入院患者中,有494例成年钝性伤患者从现场启动了TTA。单因素分析中与死亡率相关的变量(HzR;95%置信区间)包括SBP<90(9.4;4.2,21.2)、RR>29或<10(17.8;4.8,66.0)、插管状态(4.5;2.3,8.9)和GCS<8(9.7;4.8,19.9)。当在多变量模型中同时评估多个预测因素时,SBP<90和GCS<8似乎是最强的死亡率预测因素(在存在SBP和GCS的情况下,RR和插管情况无统计学意义)。三级系统识别出ISS增加和早期(≤4周)死亡风险增加的患者。L1组和L2组在38天时的生存率有统计学显著差异,但在>38天时无差异(p = 0.739)。
TTA标准筛选出了ISS更高和早期死亡率更高的患者,但对长期生存的影响可能并不明显。钝性伤的完全TTA标准可能限于GCS<8、SBP<90、RR>29或<10以及插管状态。